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22.777 Keywords • 48.564 Synonyms • 5.298 Translations • 7.910 Pronunciations • 151.062 Cross-references

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ADH

Abbreviation for alcohol dehydrogenases. These are occurring in the human liver (and also in the digestive tract) enzymes in the presence of the coenzyme NAD (nicotinamide adenine dinucleotide, which acts as a hydrogen carrier) alcohol degrades and to acetaldehyde oxidized. This is biologically activated with the help of the enzyme ALDH (aldehyde dehydrogenase) acetic acid detoxifies and ultimately to carbon dioxide and water, whereby the concentration of free acetaldehyde in the body normally remains very low. In East Asians, the indigenous peoples of the Americas (Indians) and the Aborigines of Australia ALDH is inactive in around 80% of the cases, so these ethnic groups tolerate only small amounts of alcohol. In Europeans, this alcohol intolerance occurs only in about 5% of the population.

ADH are also in the yeasts available; Yeast ADH is used to determine the Blood alcohol content used. There are two reasons why women tolerate less alcohol than men. On the one hand, this is due to the lower body weight and higher body fat content. And on the other hand, the female liver also needs to break down sex hormones. When estrogen decreases during menopause, more alcohol is tolerated by women. In the splitting of larger amounts of alcohol methanol (Wood spirit) it can contribute to the formation of toxic formic acid come. See further information or keywords on the subject below health,

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