The vineyard is located in the commune of Saint-Estèphe in the Médoc (Haut-Médoc) directly on the communal border with Pauillac. In the 1855 Bordeaux classification, it was awarded fifth place (Cinquième Grand Cru Classé). The vineyards were expropriated from the Château Cos d'Estournel opposite in 1789 in connection with the French Revolution. The first owner was François Labory from 1800 to 1840, who gave the estate its current name. The "Cos" part of the name is derived from the district name "Caux" (gravelly hill). In 1845, Louis-Gaspard Estournel (1753-1844) bought back the estate, but sold it seven years later to the English banker Charles Martyns. In 1958, it was acquired by the Audoy family of Argentinian descent. The vineyards of Château Cos Labory cover 18 hectares and are planted with Cabernet Sauvignon (60%), Merlot (35%), Cabernet Franc (10%) and Petit Verdot (5%). The long-lasting red wine is matured for up to 15 months in 50% new barriques. The second wine is called "Le Charme Labory".
The estate also includes Château Andron Blaquet, one of the oldest wine estates in Saint-Estèphe, which was acquired in 1971. Due to a lack of descendants, the Audoy family sold the estate to their neighbour Michel Reybier, the owner of Château Cos d'Estournel, the former sister estate of Château Cos Labory, in 2023. The purchase price was not disclosed. With the purchase of Château Cos Labory, the historic vineyard of Château Cos d'Estournel, as it existed at the time of the Bordeaux classification in 1855, was restored.
