The appellation is in the wine-growing region Loire in a semicircle to the east and southeast around the city of Nantes in the area Pays Nantais on the Atlantic coast. The former VDQS area was classified as AOP in 2012. The name derives from the main grape variety Gros Plant ab, a synonym used here for those from the 14th century Charente imported variety Folle Blanche, The wine made from it was particularly popular with the Dutch and became partly for the distillation used. From the mid-1880s, the phylloxera Disaster almost completely eradicated the Folle Blanche and through Melon de Bourgogne and hybrid grape replaced. The variety was only reactivated by setting up the appellation and the EU ban on hybrids.
The vineyards cover 2,300 hectares of vineyards on stony soils mixed with igneous rock on sunny slopes in a total of 94 municipalities in the three departments of Loire-Atlantique, Maine-et-Loire and Vendée. Much of the area overlaps with the appellation Muscadet, The Atlantic climate is shaped by the nearby sea. The white wines will unmixed made from the Gros Plant (Folle Blanche) variety. The designation Gros Plant du Pay Nantais sur lie may be used if the wines after fermentation are at least until March 1st of the year following the harvest lees to store. The bottling usually takes place immediately after racking however no later than November 30 of the year following the harvest. Well-known producers include Domaine de Beauregard, Château de Briacé, Domaine de la Cognardière, Château de Fromenteau, Château de la Preuille and Clos Saint-Vincent des Rongères.