The 527 km long river (also Maa, Mää and Mee) originates from a confluence of the two source rivers White Main (Fichtelgebirge) and Red Main (Frankish Alb) in Bavaria- Germany, The longest right tributary of the Rhine flows through the wine-growing region in a large W-shape between Aschaffenburg and Schweinfurt Franconia, All vineyards are on south facing valley slopes on the riverbanks of the Main or in side valleys of its tributaries (Franconian Saale, Kinzig, Nidda, Regnitz, Tauber ). After the flow of the metropolitan areas Würzburg and Frankfurt am Main It ends in front of the old town of Mainz between Ginsheim-Gustavsburg and the Wiesbaden district Mainz-Kostheim in the Rhine.
The course of the Main in Lower Franconia forms two conspicuous geometrical landscape forms, so to speak, namely the Maindreieck and the Mainviereck, which gave their name to two Franconian winegrowing areas. A large part of the Franconian vineyards with about 4,200 hectares of vineyards is located directly on or around the Maindreieck. A special feature here is the wine island in the district of Kitzingen between an original arm of the Main (Altmain) and the Main Canal between Volkach and Gerlachshausen. Viticulture is practiced on this human-influenced island. The Mainviereck covers only 330 hectares of vineyards. Like all in principle waters the Main exerts a climate-regulating, positive influence on viticulture.